The benefits of Ozempic and Wegovy are well-known; they are considered one of the best medicines for weight loss and diabetes control. Ozempic is a kind of injection that treats diabetic 2 patients and is used to treat weight control through these medicines. People reported relief in heart disease, and kidney problems too. Many overweight patients are reported with high blood pressure, fatty liver, rheumatoid arthritis, and sleep apnea. Doctors are suggesting that being overweight is the primary cause of these diseases. These drugs can reduce joint pain.
What is the GLP-1 drug?
According To Director & Senior Consultant (Orthopaedics) (Dharamshila Narayana Superspeciality Hospital Delhi) Renowned Joint Replacement Surgeon Dr. B.S Murthy, “These drugs act as the action of a hormone called glucagon-like peptide 1. When the sugar level starts rising this drug stimulates the body to produce insulin. Extra insulin helps to reduce sugar levels In research on GlP-1 scientists observed that this drug is not only used to produce insulin and reduce obesity but is also effective for other problems like Rheumatic arthritis. People across the world reported that after taking ozempic they experienced less joint pain.”
What Research & Study Indicates?
A 2021 research review showed a possible relationship between forms of inflammatory arthritis and insulin-related metabolic abnormalities. In addition, there is a relationship between insulin resistance and Rheumatic arthritis disease activity.
Recently, Three preclinical studies were included in the 2024 review, which examined how GLP-1 analogs can treat Rheumatic Arthritis Preclinical studies have shown different anti-inflammatory effects of GLP-1 analogs on human fibroblast-like synoviocytes. According to the above review, all three studies have highlighted that GLP-1 analogues can work to treat Rheumatic Arthritis by inhibiting the nuclear factor kappa-light-chain-enhancer of the activated B cell pathway, thereby reducing immune responses.
GLP-1 Receptor’s agonist approved by the Food and Drug Department (USA)
1- semaglutide (Rybelsus, Ozempic, Wegovy)
exenatide (Bydureon BCise, Byetta)
lixisenatide (Adlyxin)
lixisenatide/insulin glargine (Soliqua)
liraglutide (Saxenda, Victoza)
liraglutide/insulin degludec (Xultophy)
dulaglutide (Trulicity)
Precautions for GLP-1
1. You shouldn’t take GLP-1 drug if you are pregnant or planning for a baby
2. GLP-1 receptor agonists aren’t recommended for you if you are hypersensitive to GLP-1
3. You should not take this if you are living with a severe condition, like inflammatory bowel disease
4. You should not take this if you are at thyroid risk
5. Never take it without consulting with your doctor
GLP-1 drug is in your kitchen
1. Healthy food :- Certain fats are healthy for your body and naturally contain GLP-1 like monosaturated fatty acids and omega-3 fatty acids. These types of fats are found in fish, avocado and avocado oil, flaxseed and flaxseed oil.
2. Lean protein :- Lower-fat sources of protein can increase GLP-1 and also maintain muscle mass. Since GLP-1 medications often cause loss of muscle mass along with body fat. You can get high protein from chicken, cottage cheese and soybean.
3. Soluble fibre :- it’s a better option to choose soluble fibres. You can get soluble fibre from fruits, vegetables, whole grains, and legumes.
Mimic Supplements
According to Dr. B.S murthy these are the supplements of GLP-1 drug.
1. Psyllium: Psyllium is one of the best sources of soluble fibre, taking psyllium powder can also increase GLP-1
2. Curcumin: Curcumin is a compound found in turmeric which is easily found in our kitchen. Studies in animals show that curcumin can improve blood sugar control by increasing GLP-1 release.
3. Ginseng : it is a medicinal plant mainly used to stimulate cognitive abilities. this may also be possible that it increases GLP-1.
4. Probiotics : It’s essential to add probiotics to your diet through which it can help produce GLP-1 naturally.
Note: You should not take any medicine or drug without consulting your physician.
1 Comment
Well done!